By Harald O. Heymann DDS, MEd
COMPOSITION AND EFFICACY
G5 is a time and research proven desensitizer that works to prevent post-op sensitivity when placed under virtually any type of dental restoration. Based historically on the formulation of a dentin primer, G5 contains 5% glutaraldehyde, 35% HEMA, and water: a simple but highly effective composition.
Achieving optimal isolation prior to any cementation procedure is essential.
Prior to crown cementation, remove the temporary crown and clean the preparation of residual cement and debris. Air dry.
Using a microbrush, apply G5 sparingly using a scrubbing action on all surfaces of the tooth preparation for 30 seconds. (FIG. 1) Avoid contact of G5 with soft tissue.
After application, rinse the residual G5 from the tooth with a gentle stream of water for 5 seconds. (FIG. 2)
If using GI, RMGI, Zinc Phosphate or other non-bonding cements, blot away excess moisture and proceed with cementation according to manufacturer’s instructions.
If using a conventional adhesive resin cement, air dry or leave moist according to manufacturer’s instructions.
Apply G5 sparingly to avoid soft tissue contact. Scrub on the preparation for 30 seconds.
When rinsing, use a gentle stream of water to avoid soft tissue contact.
HOW DOES G5 WORK?
- G5 is bactericidal owing to the glutaraldehyde. Like chlorhexidine and other cavity disinfectants, it kills the “bugs.”
- Unlike most cavity disinfectants and desensitizers, G5 forms a series of “coagulation plugs” in the dentinal tubules, thereby reducing dentin permeability and fluid flow, critical keys to desensitization (based on Brännström’s Hydrodynamic Theory of Dental Pain). G5 does so by coagulating the plasma proteins (serum albumin) in the dentinal tubules.
- G5 is a very effective cross-linking agent (flocculant) that toughens the collagen to which dental primers bond through hybrid layer formation.
- G5 also has been shown to effectively resist the adverse effects of MMPs, proteolytic enzymes that if activated can deteriorate the dentin/resin bond.
It should be pointed out that G5 does not adversely effect bond strengths of any resin bonding agent or of any cement. It is unique among desensitizers in this regard.